Bovine Type I Collagen Wound Matrix with 45S5 Bioactive Glass

A Collagen–Bioglass Wound Matrix

NOVASHIELD® is a bovine type I collagen wound matrix combined with 45S5 bioactive glass. It is designed for the management of wounds, supporting the wound environment through its material composition and structure.

Key Features of NOVASHIELD®

NOVASHIELD™ Wound Matrix is designed to support wound management through its material composition and handling characteristics.

Key Features of NOVASHIELD®

NOVASHIELD™ Wound Matrix is designed to support wound management through its material composition and handling characteristics.

First 510(k) wound product containing collagen + bioactive glass

Highly absorbent material and easy to manipulate

Bovine type I collagen combined with 45S5 bioactive glass

510(k) cleared – June 2023

Provisional patent filed

3-year shelf life (data on file)

SKU Description Sizes HCPCS
WM1011SP
NovaShield Wound Matrix

1cm x 1cm

A2045

WM1022SP
NovaShield Wound Matrix

2cm x 2cm

A2045

WM1033SP

NovaShield Wound Matrix

3cm x 3cm

A2045

WM1044SP
NovaShield Wound Matrix

4cm x 4cm

A2045

WM0122SP
NovaShield Wound Matrix
5cm x 5cm
A2045
WM0123SP
NovaShield Wound Matrix

5cm x 8cm

A2045

WM0133SP

NovaShield Wound Matrix

8cm x 8cm

A2045

WM0145SP

NovaShield Wound Matrix

10cm x 12cm

A2045

Observed Outcomes

Associated with a noticeable reduction in deep wound bed inflammation in a porcine full thickness wound model (compared to Endoform).¹

Collagen–Bioglass Matrix Advantages

Supporting key challenges in the wound healing environment.

  1. Data on file
  2. Naseri, Shiva, William C. Lepry, and Showan N. Nazhat. “Bioactive glasses in wound healing: hope or hype?” Journal of Materials Chemistry B 5, no. 31 (2017): 6167-6174.
  3. Qi, Quan, Yanlun Zhu, Gang Liu, Zhize Yuan, Haiyan Li, and Qiang Zhao. “Local intramyocardial delivery of bioglass with alginate hydrogels for post-infarct myocardial regeneration.” Biomedicine & Pharmacotherapy 129 (2020): 110382.
  4. Li, Ying, Xin Zhang, Dan He, Zhijie Ma, Ke Xue, and Haiyan Li. “45S5 Bioglass® works synergistically with siRNA to downregulate the expression of matrix metalloproteinase-9 in diabetic wounds.” Acta Biomaterialia 145 (2022): 372-389.
  5. Dong, Xin, Jiang Chang, and Haiyan Li. “Bioglass promotes wound healing through modulating the paracrine effects between macrophages and repairing cells.” Journal of Materials Chemistry B 5.26 (2017): 5240-5250.
  6. Brett, David. “A review of collagen and collagen-based wound dressings.” Wounds 20, no. 12 (2008): 347-356.

Collagen–Bioglass Matrix Advantages

Supporting key challenges in the wound healing environment.

  1. Data on file
  2. Naseri, Shiva, William C. Lepry, and Showan N. Nazhat. “Bioactive glasses in wound healing: hope or hype?” Journal of Materials Chemistry B 5, no. 31 (2017): 6167-6174.
  3. Qi, Quan, Yanlun Zhu, Gang Liu, Zhize Yuan, Haiyan Li, and Qiang Zhao. “Local intramyocardial delivery of bioglass with alginate hydrogels for post-infarct myocardial regeneration.” Biomedicine & Pharmacotherapy 129 (2020): 110382.
  4. Li, Ying, Xin Zhang, Dan He, Zhijie Ma, Ke Xue, and Haiyan Li. “45S5 Bioglass® works synergistically with siRNA to downregulate the expression of matrix metalloproteinase-9 in diabetic wounds.” Acta Biomaterialia 145 (2022): 372-389.
  5. Dong, Xin, Jiang Chang, and Haiyan Li. “Bioglass promotes wound healing through modulating the paracrine effects between macrophages and repairing cells.” Journal of Materials Chemistry B 5.26 (2017): 5240-5250.
  6. Brett, David. “A review of collagen and collagen-based wound dressings.” Wounds 20, no. 12 (2008): 347-356.

Documents and Downloads

Explore NOVASHIELD® resources, including product features, indications, and specifications. Download the overview to learn more.

Product Overview

Join Us in Transforming Wound Care!

We are excited to embark on this journey and we invite wound care professionals and providers alike to join us. Together, we can make a difference in the lives of patients and create a brighter future. Contact us today to learn more about how Total Ancillary can help.